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Kidney disease treatment & trial finder

Choose your kidney diagnosis to see recently approved treatments and actively enrolling clinical trials for that condition — with plain-language evidence and links to ClinicalTrials.gov.

For information only — not medical advice. Always talk to your nephrologist.

Kidney treatment is advancing fast

17 FDA-approved therapies since 2018 8 in the last two years — plus 3 trials enrolling now.

17
Approved therapies
3
Trials enrolling
9
Conditions covered
1
1
5
1
1
6
2
18
19
20
21
22
23
24
25
26

New U.S. FDA approvals for a kidney indication, by year — across IgA nephropathy, lupus nephritis, C3 glomerulopathy, FSGS, diabetic and polycystic kidney disease, and more. Sources on each treatment card below. Verified July 2026.

Type
Common conditions

Treatment Options for Your Diagnosis

1

Foundational care

Start here

Blood-pressure control with ACE inhibitors or ARBs, and SGLT2 inhibitors, are standard first-line therapy for most CKD. Your nephrologist typically starts here.

These are newer and recently approved therapies for Membranous nephropathy — not the full standard of care. Ask your care team whether any fit your situation.

Genentech / Roche logo
Genentech / Roche
Rituximab (Rituxan)
FDA approved (used off-label)

Anti-CD20 B-cell depleting antibody

MENTOR

Evidence: Superior remission and anti-PLA2R antibody depletion vs cyclosporine at 24 months.

View the MENTOR study on ClinicalTrials.gov

Source: MENTOR trial, NEJM 2019 (rituximab is not FDA-labeled for this use)Verified 2026-07-18

Clinical Trials Related to Your Diagnosis

1

Actively enrolling studies related to Membranous nephropathy. Whether a trial is right for you — and whether you qualify — is decided by the study team together with your nephrologist.

Biogen logo
Biogen
Felzartamab
Enrolling
PROMINENTPhase 3

Testing felzartamab (an anti-CD38 antibody) against tacrolimus in adults with primary (anti-PLA2R) membranous nephropathy. Earlier-phase data showed rapid anti-PLA2R antibody reductions.

Eligibility is determined by the study team and your nephrologist.

View the PROMINENT on ClinicalTrials.gov

Source: M-PLACE Phase 2 data (Biogen)Verified 2026-07-18

Browse all recruiting Membranous nephropathy trials on ClinicalTrials.gov

For information only — this is not medical advice, and nothing here is a recommendation to start, stop, or switch treatment. Every treatment decision should go through your nephrologist.

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