Choose your kidney diagnosis to see recently approved treatments and actively enrolling clinical trials for that condition — with plain-language evidence and links to ClinicalTrials.gov.
For information only — not medical advice. Always talk to your nephrologist.
17 FDA-approved therapies since 2018 — 8 in the last two years — plus 3 trials enrolling now.
New U.S. FDA approvals for a kidney indication, by year — across IgA nephropathy, lupus nephritis, C3 glomerulopathy, FSGS, diabetic and polycystic kidney disease, and more. Sources on each treatment card below. Verified July 2026.
Blood-pressure control with ACE inhibitors or ARBs, and SGLT2 inhibitors, are standard first-line therapy for most CKD. Your nephrologist typically starts here.
These are newer and recently approved therapies for Membranoproliferative GN / C3 glomerulopathy — not the full standard of care. Ask your care team whether any fit your situation.
Oral factor B inhibitor (complement pathway)
Evidence: 35.1% proteinuria reduction vs placebo; eGFR stabilized and C3 deposits reduced over 12 months.
Source: FDA prescribing information; APPEAR-C3G, Lancet 2025Verified 2026-07-18
Targeted C3 complement inhibitor
Evidence: 68% proteinuria reduction vs placebo at 26 weeks; 71% cleared C3 deposits.
Source: FDA prescribing information; VALIANT, NEJM 2025Verified 2026-07-18
Actively enrolling studies related to Membranoproliferative GN / C3 glomerulopathy. Whether a trial is right for you — and whether you qualify — is decided by the study team together with your nephrologist.
No actively enrolling trials we're tracking for Membranoproliferative GN / C3 glomerulopathy right now.
For information only — this is not medical advice, and nothing here is a recommendation to start, stop, or switch treatment. Every treatment decision should go through your nephrologist.
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